The Role of Obesity in enhancing Inflammatory Process in Knee Osteoarthritis Patients
Keywords:
Knee osteoarthritis, inflammatory markers, obesity, body mass index (BMI), ESRAbstract
Knee osteoarthritis (KOA) is one of the most frequent diseases in orthopedic clinic, and obesity is the most important risk factors of it. The studied sample consisted of 85 patients with KOA - proven by simple X-Ray- from the patients attending the orthopedic clinic in Idlib University Hospital, KOA was more common in patients whose ages ranged between (27-70 years), 70.6% of the study samples were females, and the left knee was the most affected, 73% of the samples had a BMI >30, 82% of samples had radiological Kellgren-Lawrence class II and III.
The results showed that the average of body mass index (BMI) in females with KOA was 35.75 ± 5.48 kg / m2, while the average in males was 29.25 ± 5.46 kg / m2, 60% of women with KOA had a BMI of more than 35 kg / m2.
the mean of the erythrocyte sedimentation rate was 25.5 ± 17.18 mm/h1, and the results of the statistical analysis showed a significant correlation between the values of ESR in patients with KOA on the one hand and sex (r = 0.565, P < 0.001), and BMI (r = 0.218, P = 0.046) on the other hand.
In patients with KOA and ESR>30, 91.33% of them were female (P<0.001) and 83.33% of them were obese (BMI>=30).
